Author

S. K. S. Chu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

J. B. Siegel· 2 shared C. Duan· 1 shared H. N. Frizzo· 1 shared J. S. Fell· 1 shared M. P. Connolly· 1 shared P. Huang· 1 shared R. W. Caster· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. B. Siegel

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintAug 20, 2020

Computationally Guided Design of BCR-ABL Tyrosine Kinase Inhibitors

C. Duan, S. K. S. Chu, J. B. Siegel, J. S. Fell

The paper designs two new BCR-ABL tyrosine kinase inhibitors with predicted improved binding affinity over imatinib for advanced chronic myeloid leukemia treatment.

DOI 10.1101/2020.08.20.259887

humancomparative / phylogenetic analysis

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 28, 2019

Evaluating molecular modeling tools for thermal stability using an independently generated dataset

P. Huang, S. K. S. Chu, H. N. Frizzo…·J. B. Siegel

The paper evaluates five computational tools for predicting thermal stability and soluble protein production in enzyme mutants using an expanded dataset of 51 β-glucosidase mutants.

DOI 10.1101/856732

protein structurestatistical model

𝕏 PostBluesky