ImmunologybioRxivPreprint
Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction
C. Li, S. K. Ture, B. Nieves…·C. N. Morrell
This study shows that thrombocytopenia causes monocyte immune dysfunction through platelet-monocyte CD47 interactions, leading to increased TLR responses and altered immunometabolism.