Author

S. Kaeppeli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Jermakowicz· 1 shared A. M. Kurimchak· 1 shared C. Cantu· 1 shared C. Gentili· 1 shared C. Koenig· 1 shared F. Bourgain-Guglielmetti· 1 shared G. Cozza· 1 shared G. Ribaudo· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. M. Jermakowicz

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RAPID RESISTANCE TO BET INHIBITORS IS MEDIATED BY FGFR1 IN GLIOBLASTOMA

A. M. Jermakowicz, A. M. Kurimchak, K. J. Johnson, F. Bourgain-Guglielmetti, S. Kaeppeli, M. Affer, H. Pradhyumnan, R. Suter, W. Walters, M. Cepero, J. Duncan, N. G. Ayad

This study identifies rapid resistance to BET inhibitors in glioblastoma mediated by FGFR1 and shows that co-targeting BET and FGFR1 synergizes to reduce tumor growth.

bioRxiv · Dec 19, 2023Cancer Biology

Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and cell death

Z. Kabakci, S. Kaeppeli, G. Cozza, C. Cantu, C. Koenig, J. Toggweiler, C. Gentili, G. Ribaudo, G. Zagotto, K. Basler, L. A. Pinna, S. Ferrari

This study identifies CDC25 inhibitors that induce cell cycle arrest and cell death through a mixed-type mechanism, validated in 2D cultures and 3D organoids.

bioRxiv · Apr 27, 2018Cancer Biology