Author

J. Duncan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

K. J. Johnson· 2 shared A. Hong· 1 shared A. J. Nunn· 1 shared A. M. Jermakowicz· 1 shared A. M. Kurimchak· 1 shared ALL ON MAIN LIST· 1 shared D. Sharipova· 1 shared E. Y. Skolnik· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

K. J. Johnson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RAPID RESISTANCE TO BET INHIBITORS IS MEDIATED BY FGFR1 IN GLIOBLASTOMA

A. M. Jermakowicz, A. M. Kurimchak, K. J. Johnson, F. Bourgain-Guglielmetti, S. Kaeppeli, M. Affer, H. Pradhyumnan, R. Suter, W. Walters, M. Cepero, J. Duncan, N. G. Ayad

This study identifies rapid resistance to BET inhibitors in glioblastoma mediated by FGFR1 and shows that co-targeting BET and FGFR1 synergizes to reduce tumor growth.

bioRxiv · Dec 19, 2023Cancer Biology

Identification of Wee1 as Target in Combination with Avapritinib for the Treatment of Gastrointestinal Stromal Tumors

S. Ye, D. Sharipova, M. Kozinova, L. Klug, J. D'Souza, M. G. Belinsky, K. J. Johnson, M. B. Einarson, K. Devarajan, Y. Zhou, S. Litwin, M. C. Heinrich, R. DeMatteo, M. von Mehren, J. Duncan, L. Rink

This study identifies Wee1 as a therapeutic target in combination with avapritinib for treating gastrointestinal stromal tumors (GIST) by analyzing kinome profiles and conducting functional assays.

bioRxiv · Jun 7, 2020Cancer Biology

Discoidan Domain Receptor 1 (DDR1) Tyrosine Kinase is Upregulated in PKD Kidneys But Does Not Play a Role in the Pathogenesis of Polycystic Kidney Disease

E. Y. Skolnik, I. Soomro, A. Hong, Z. Li, J. Duncan, ALL ON MAIN LIST

This study identifies DDR1 as upregulated in ADPKD but shows it does not contribute to disease progression, ruling it out as a therapeutic target.

bioRxiv · Jan 22, 2019Cell Biology

Drug prescription pattern in European neonatal units

I. Mesek, G. Nellis, J. Lass, T. Metsvaht, H. Varendi, H. Visk, M. A. Turner, A. J. Nunn, J. Duncan, I. Lutsar

This study describes drug use in European neonatal units and finds that gestational age and geographic region influence prescription patterns.

bioRxiv · Nov 5, 2018 · PreprintPharmacology & Toxicology