Cancer BiologybioRxiv
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and cell death
Z. Kabakci, S. Kaeppeli, G. Cozza…·S. Ferrari
This study identifies CDC25 inhibitors that induce cell cycle arrest and cell death through a mixed-type mechanism, validated in 2D cultures and 3D organoids.
DOI 10.1038/s41598-019-38579-7