BiochemistrybioRxiv
Precision targeting of the Plasminogen Activator Inhibitor-1 mechanism increases efficacy of fibrinolytic therapy in empyema.
G. Florova, R. A. Girard, A. O. Azghani…·A. A. Komissarov
The paper demonstrates that targeting PAI-1 with DSP reduces the required dose of tPA/uPA in empyema treatment without bleeding complications in rabbit models.
DOI 10.14814/phy2.14861