Author

S. Keary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

M. F. Garcia-Parajo· 2 shared A. Guevara-Garcia· 1 shared A. Sosa-Costa· 1 shared C. Manzo· 1 shared F. Campelo· 1 shared I. Piechocka· 1 shared J. Stanisavljevic· 1 shared K. Borgman· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

M. F. Garcia-Parajo

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2 papers

Recent·Most cited

Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions

S. Keary, A. Guevara-Garcia, N. Mateos, F. Campelo, M. F. Garcia-Parajo

The paper uses super-resolution microscopy to show that integrin nanoclusters are spatially segregated within focal adhesions, suggesting coordinated activation through adaptor nanoclusters.

bioRxiv · Dec 16, 2023 · PreprintCell Biology

Shear flow-driven actin re-organization induces ICAM-1 nanoclustering on endothelial cells that impact T-cell migration

I. Piechocka, S. Keary, A. Sosa-Costa, L. Lau, N. Mohan, J. Stanisavljevic, K. Borgman, M. Lakadamyali, C. Manzo, M. F. Garcia-Parajo

This study shows that shear forces induce ICAM-1 nanoclustering on endothelial cells through actin re-organization, enhancing T-cell migration by strengthening adhesion and reducing actin retrograde flow.

bioRxiv · Jun 29, 2020 · PreprintCell Biology