Lung spatial profiling reveals a T cell signature in COPD patients with fatal SARS-CoV-2 infection
C. X. Yang, M. Tomchaney, M. F. Landecho, B. Recalde, M. M. Oto, J. Zulueta, J. Malo, S. Knoper, M. Contoli, A. Papi, D. Vasilescu, M. Sauler, C. Straub, C. Tan, F. D. Martinez, , F. Polverino
The paper uses spatial transcriptomic and proteomic profiling to analyze lung tissues from COPD patients who died of COVID-19, revealing increased T-lymphocytes and altered immune responses.
bioRxiv · Apr 20, 2022Immunology