Author

F. Polverino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Papi· 2 shared F. D. Martinez· 2 shared F. Kheradmand· 2 shared J. Malo· 2 shared M. Contoli· 2 shared M. Tomchaney· 2 shared S. Knoper· 2 shared A. De Leo· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Papi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lymphatic Dysfunction Models an Autoimmune Emphysema Phenotype of Chronic Obstructive Pulmonary Disease

B. Summers, K. Kim, T. M. Lu, S. Houghton, J. R. Quintero, J. Cala-Garcia, T. Pannellini, F. Polverino, R. Lis, A. Trivedi, H. O. Reed

This study shows that lymphatic dysfunction drives lung injury and autoimmune emphysema in COPD by promoting TLO formation and autoantibody production in mice, with similar patterns observed in human COPD patients.

bioRxiv · Oct 31, 2023 · PreprintPathology

Lung spatial profiling reveals a T cell signature in COPD patients with fatal SARS-CoV-2 infection

C. X. Yang, M. Tomchaney, M. F. Landecho, B. Recalde, M. M. Oto, J. Zulueta, J. Malo, S. Knoper, M. Contoli, A. Papi, D. Vasilescu, M. Sauler, C. Straub, C. Tan, F. D. Martinez, , F. Polverino

The paper uses spatial transcriptomic and proteomic profiling to analyze lung tissues from COPD patients who died of COVID-19, revealing increased T-lymphocytes and altered immune responses.

bioRxiv · Apr 20, 2022Immunology

A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc

F. Souvalidou, D. Boi, R. Montanari, F. Polverino, G. Marini, D. Capelli, G. Pochetti, R. Contestabile, D. Trisciuoglio, A. Tramonti, P. Carpinelli, C. Ascanelli, C. Lindon, A. De Leo, R. Di Santo, , A. Paiardini

This study identifies PHA-680626 as an amphosteric inhibitor that disrupts the AURKA/N-Myc interaction, reducing N-Myc levels and cell viability in neuroblastoma cells.

bioRxiv · Mar 10, 2021 · PreprintCancer Biology

Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease

M. Tomchaney, M. Contoli, J. Mayo, S. Baraldo, S. Li, C. Cabel, D. Bull, S. Lick, J. Malo, S. Knoper, S. Kim, J. Tram, J. Rojas Quintero, M. Kraft, J. Ledford, , F. Polverino

This study examines how cigarette smoke and COPD affect SARS-CoV-2 infection by analyzing ACE2 and TMPRSS2 expression in human and mouse lung tissues and an in vitro model.

bioRxiv · Dec 7, 2020 · PreprintImmunology