Pharmacology & ToxicologybioRxivPreprint
DIETARY MONOTERPENOIDS AS A NEW CLASS OF ALLOSTERIC HUMAN ARYL HYDROCARBON RECEPTOR ANTAGONISTS
K. Poulikova, I. Zuvalova, B. Vyhlidalova…·Z. Dvorak
The paper identifies carvones as non-competitive allosteric antagonists of the AhR, inhibiting target gene induction in a ligand-selective and cell type-specific manner.
DOI 10.1101/2020.11.30.404178