Efflux pump mutations in Pseudomonas aeruginosa cause low-level clinical resistance and high-level tolerance to antibiotics in patients
P. Laborda, S. Lolle, S. Hernando-Amado, M. Alcalde-Rico, J. L. Martinez, S. Molin, H. K. Johansen
This study shows that mexZ mutations in Pseudomonas aeruginosa lead to antibiotic tolerance and altered colonization in human airway models through overexpression of lecA.
bioRxiv · Aug 18, 2023 · PreprintMicrobiology