Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants
A. O. Adegoke, G. Thangavelu, T.-F. Chou, M. Petersen, K. Kakugawa, J. May, K. Joannou, Q. Wang, K. K. Ellestad, L. Boon, P. A. Bretscher, H. Cheroutre, M. Kronenberg, T. A. Baldwin, C. C. Anderson
This study identifies a regulatory pathway between BTLA and CD5 in T cells that calibrates their expression to establish self-tolerance in recent thymic emigrants.
Open Biology · Oct 30, 2024Peer-reviewedImmunology