Author

S. Ly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Ecology· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

S. Lay· 3 shared E. A. Karlsson· 2 shared J. A. Bohl· 2 shared J. E. Manning· 2 shared P. Dussart· 2 shared S. Chea· 2 shared S. Heng· 2 shared T. Cantaert· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

S. Lay

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

First-in-human evaluation of cutaneous innate and adaptive immunomodulation by mosquito bites

D. Guerrero, H. T. M. Vo, C. Lon, J. A. Bohl, S. Nhik, S. Chea, S. Man, S. Sreng, A. R. Pacheco, S. Ly, R. Sath, S. Lay, D. Misse, R. Huy, R. Leang, , J. E. Manning

This study evaluates immune responses to mosquito bites in humans, identifying key genes, cell types, and pathways involved in innate and adaptive immunity.

bioRxiv · Apr 25, 2022 · PreprintImmunology

Robust and Functional Immunity up to 9 months after SARS-CoV-2 infection: a Southeast Asian longitudinal cohort

H. M. T. Vo, A. Maestri, S. Lay, S. Sann, N. Ya, L. Sovann, S. Sopheak, P. Pean, H. Auerswald, O. Schwartz, T. Bruel, S. Heng, P. Dussart, S. Ly, V. Duong, , T. Cantaert

The paper evaluates immune responses up to 9 months post-SARS-CoV-2 infection in a Cambodian cohort, showing sustained functional immunity without re-infection.

bioRxiv · Aug 12, 2021Immunology

Field efficacy of guppies and pyriproxyfen (Sumilarv(R) 2MR) combined with community engagement on dengue vectors in Cambodia: a randomized controlled trial

J. C. Hustedt, D. Doum, V. Keo, S. Ly, B. Sam, V. Chan, N. Alexander, J. Bradley, M. Liverani, D. B. Prasetyo, A. Rachmat, M. Shafique, S. Lopes, L. Rithea, J. Hii

This study evaluates the effectiveness of guppies and pyriproxyfen combined with community engagement in reducing dengue vector populations in Cambodia, finding significant reductions in adult female Aedes density.

bioRxiv · May 15, 2020Ecology

Rapid metagenomic characterization of a case of imported COVID-19 in Cambodia

J. E. Manning, J. A. Bohl, S. Lay, S. Chea, S. Ly, Y. Sengdoeurn, S. Heng, C. Vuthy, K. Kalantar, V. Ahyong, M. Tan, J. Sheu, C. M. Tato, J. DeRisi, L. Baril, , E. A. Karlsson

The paper describes using metagenomic sequencing and an open-source pipeline to rapidly characterize Cambodia's first COVID-19 case.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology

Long-term impact of intensive postgraduate laboratory training at the Cold Spring Harbor Neurobiology of Drosophila summer course

S. Ly, K. Kaun, C.-H. Lee, D. Stewart, S. R. Pulver, A. C. Keene

This paper evaluates the long-term impact of a postgraduate Drosophila neuroscience summer course on participants' careers and scientific training.

bioRxiv · Jun 20, 2019 · PreprintScientific Communication & Education

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

M. F. Osborn, A. H. Coles, A. Biscans, R. A. Haraszti, L. Roux, S. Davis, S. Ly, D. Echeverria, M. R. Hassler, B. M. D. C. Godinho, M. Nikan, A. Khvorova

This study shows that lipid conjugation affects siRNA hydrophobicity, influencing its distribution via lipoprotein pathways and enabling tissue-specific mRNA silencing without toxicity.

bioRxiv · Mar 23, 2018Pharmacology & Toxicology