Cancer BiologybioRxivPreprint
Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment
C. Strelez, R. Perez, J. S. Chlystek…·S. M. Mumenthaler
This paper combines patient-derived organoids with a microfluidic organ-on-chip system to study colorectal cancer invasion under mechanical and GABAergic influences, showing enhanced invasiveness in KRAS mutant tumors.
DOI 10.1101/2023.09.14.557797