VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer
N. Poulose, A. Polonski, N. Forsythe, G. Gregg, S. Maguire, M. Fuchs, S. Minner, S. S. McDade, I. Mills
This study identifies VPRBP as a co-regulator of the androgen receptor and OGT that suppresses p53 activation in prostate cancer, linking its expression to poor clinical outcomes.
bioRxiv · Feb 28, 2021Cancer Biology