Author

I. Mills

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 5 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. Steele· 3 shared S. S. McDade· 3 shared A. Pickard· 2 shared D. Mukherjee· 2 shared D. Waugh· 2 shared F. Amoroso· 2 shared K. Butterworth· 2 shared S. Jain· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCancer Biology

R. Steele

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

IRF7 impacts on prostate cancer cell survival in response to radiation

A. Pickard, F. Amoroso, K. McCulloch, A. Erickson, A. Sachdeva, R. Steele, D. Mukherjee, M. Dellett, J. McComb, L. McCaffrey, C. Hart, M. Brown, S. S. McDade, D. Waugh, N. Clarke, , I. Mills

This study investigates how IRF7 influences prostate cancer cell survival after radiation and identifies therapeutic vulnerabilities linked to IRF7 expression.

bioRxiv · Sep 23, 2022 · PreprintCancer Biology

VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer

N. Poulose, A. Polonski, N. Forsythe, G. Gregg, S. Maguire, M. Fuchs, S. Minner, S. S. McDade, I. Mills

This study identifies VPRBP as a co-regulator of the androgen receptor and OGT that suppresses p53 activation in prostate cancer, linking its expression to poor clinical outcomes.

bioRxiv · Feb 28, 2021Cancer Biology

Modulating the unfolded protein response: Impacts of radiation on the response of prostate cancer cells to ONC201

F. Amoroso, K. Glass, F. Liberal, R. Steele, S. Maguire, R. Tarapore, J. Allen, S. Van Schaeybroeck, K. Butterworth, K. Prise, J. O'Sullivan, S. Jain, D. Waugh, I. Mills

This study investigates how radiation and ONC201 modulate the unfolded protein response (UPR) in prostate cancer cells, enhancing cell death and radiosensitivity.

Scientific Reports · Feb 19, 2021Peer-reviewedCancer Biology

Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

C. Haughey, D. Mukherjee, R. Steele, A. Popple, L. Dura-Perez, A. Pickard, S. Jain, P. Mullan, R. Williams, P. Oliveira, N. Buckley, J. Honeychurch, S. S. McDade, T. Illidge, I. Mills, S. Eddie

This paper develops a novel allograft model of high-risk prostate cancer that mimics human disease features and responds to radiotherapy.

bioRxiv · Feb 16, 2020 · PreprintCancer Biology

Independence of HIF1a and androgen signaling pathways in prostate cancer

M. G. Tran, B. A. Bibby, L. Yang, F. Lo, A. Warren, D. Shukla, M. Osborne, J. Hadfield, T. Carroll, R. Stark, H. Scott, A. Ramos-Montoya, C. Massie, P. Maxwell, C. M. West, , D. Neal

The paper investigates the relationship between HIF1a and androgen signaling pathways in prostate cancer, finding they operate independently and identify shared genes associated with poor prognosis.

bioRxiv · Nov 26, 2019Cancer Biology

Tool use by four species of Indo-Pacific sea urchins

G. Barrett, D. Revell, L. Harding, I. Mills, A. Jorcin, K. M. Stiefel

The paper compares covering behavior among four Indo-Pacific sea urchin species, finding differences in material preference and depth-related cover changes, and discusses tool use interpretations.

bioRxiv · Jun 15, 2018Animal Behavior & Cognition