Cancer BiologybioRxiv
VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer
N. Poulose, A. Polonski, N. Forsythe…·I. Mills
This study identifies VPRBP as a co-regulator of the androgen receptor and OGT that suppresses p53 activation in prostate cancer, linking its expression to poor clinical outcomes.
DOI 10.1158/1541-7786.mcr-21-0477