Cancer BiologybioRxivPreprint
Transcriptional Inactivation of TP53 and the BMP Pathway Mediates Therapy-induced Dedifferentiation and Metastasis in Prostate Cancer
H. Han, Y. Wang, J. N. Curto…·F. G. Giancotti
The paper identifies a novel subtype of therapy-induced prostate cancer cells with hybrid E/M and stem-like traits, showing their dependency on HER2/3 signaling and resistance to AR inhibition.
DOI 10.1101/2021.04.14.439569