MicrobiologybioRxiv
Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases
A. A. Adhikari, T. C. Seegar, S. B. Ficarro…·A. S. Devlin
This study develops a covalent inhibitor of gut bacterial bile salt hydrolases, showing it reduces BSH activity and deconjugated bile acids in mice.
DOI 10.1038/s41589-020-0467-3