Cancer BiologybioRxiv
Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma
T. Hasan, S. P. Caragher, J. M. Shireman…·A. U. Ahmed
This study shows IL-8 promotes cellular plasticity and therapeutic resistance in glioblastoma by altering epigenetic marks and enhancing cancer initiating cell properties.
DOI 10.1038/s41419-019-1387-6