Cell BiologybioRxivPreprint
Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D
T. Isogai, K. M. Dean, P. Roudot…·G. Danuser
The paper investigates the role of actin-binding proteins in cell spreading on 2D and 3D substrates, finding that Arp2/3-vinculin binding is critical for 3D spreading but not 2D.
DOI 10.1101/756718