Author

S. Penkov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Shevchenko· 2 shared B. K. Raghuraman· 2 shared T. V. Kurzchalia· 2 shared C. Erkut· 1 shared D. Kaptan· 1 shared D. Vorkel· 1 shared E. J. Miranda Ackerman· 1 shared E. Koch· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

A. Shevchenko

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Author profile →

4 papers

Recent·Most cited

Activation of mTOR by release of extracellular cholesterol stores controls the transition from quiescence to growth in C. elegans

K. Schmeisser, D. Kaptan, B. K. Raghuraman, A. Shevchenko, S. Penkov, T. Kurzchalia

The paper shows that cholesterol release via SCL-12 and SCL-13 depletion activates mTOR, enabling C. elegans to transition from dauer quiescence to growth.

bioRxiv · Aug 26, 2022 · PreprintCell Biology

Periodic ethanol supply as a path towards unlimited lifespan of C.elegans dauer larvae

X. Zhang, S. Penkov, T. V. Kurzchalia, V. Zaburdeav

The paper proposes a mathematical model to explore how periodic ethanol supply can extend the lifespan of C. elegans dauer larvae by mitigating mitochondrial damage and toxic byproducts.

bioRxiv · Nov 17, 2021 · PreprintBiophysics

OAC-39 is an O-acyltransferase required for the synthesis of maradolipids in the dauer larva of C. elegans

S. Penkov

This study identifies OAC-39 as an O-acyltransferase required for synthesizing maradolipids in C. elegans dauer larvae.

bioRxiv · Oct 15, 2021 · PreprintBiochemistry

An insulin, AMPK, and steroid hormone-mediated metabolic switch regulates the transition between growth and diapause in C. elegans

S. Penkov, B. K. Raghuraman, C. Erkut, J. Oertel, R. Galli, E. J. Miranda Ackerman, D. Vorkel, J.-M. Verbavatz, E. Koch, K. Fahmy, A. Shevchenko, T. V. Kurzchalia

The paper shows that insulin, AMPK, and steroid hormone pathways regulate metabolic shifts during growth and diapause in C. elegans by altering enzyme ratios in central metabolic pathways.

bioRxiv · Dec 27, 2019 · PreprintBiochemistry