An insulin, AMPK, and steroid hormone-mediated metabolic switch regulates the transition between growth and diapause in C. elegans
S. Penkov, B. K. Raghuraman, C. Erkut, J. Oertel, R. Galli, E. J. Miranda Ackerman, D. Vorkel, J.-M. Verbavatz, E. Koch, K. Fahmy, A. Shevchenko, T. V. Kurzchalia
The paper shows that insulin, AMPK, and steroid hormone pathways regulate metabolic shifts during growth and diapause in C. elegans by altering enzyme ratios in central metabolic pathways.
bioRxiv · Dec 27, 2019 · PreprintBiochemistry