Single-cell transcriptome analysis reveals evolutionarily conserved features during the transition from normal breast stromal cells to cancer-associated fibroblasts
A. P. Delgado, A. Nemajerova, B. J. Nelson, M. Rao, J. Li, N. Marchenko, J. Preall, U. M. Moll, M. Egeblad, S. Powers
This study identifies conserved CAF subtypes in human and mouse breast tissues and reveals shared molecular mechanisms in their transition from normal stromal cells.
bioRxiv · May 5, 2022 · PreprintCancer Biology