H. Jing

Humanized CD36 mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36

This study creates a CD36 humanized mouse model to evaluate CD36-targeting therapies, showing that anti-CD36 antibodies inhibit tumor growth.

S-nitrosylation of Aux/IAA protein represses auxin signaling

The paper shows that S-nitrosylation of IAA17 at Cys-70 inhibits its degradation and reduces auxin signaling, affecting plant development.

Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis

The paper shows that actin filaments and membrane compression from synaptic vesicle exocytosis drive ultrafast endocytosis at synapses.

Global patterns and rates of habitat transitions across the eukaryotic tree of life

The paper investigates habitat transitions across eukaryotes, finding frequent salt barrier crossings in major lineages, with fungi showing high transition rates and suggesting non-saline habitats as ancestral.

The F-box protein AFF1 regulates ARF protein accumulation to regulate auxin response

This study identifies AFF1 as an F-box protein that regulates ARF19 stability, affecting auxin response and plant development.

Visualizing the cytosolic delivery of bioconjugated QDs into T cell lymphocytes

This study visualizes the cytosolic delivery of bioconjugated quantum dots into T cells, showing that monomeric DSS-QDs escape endosomes and exhibit higher mobility than aggregated control QDs.

Cell phone digital microscopy using an oil droplet

The paper introduces a cell phone-based microscopy method using oil droplets, showing they provide stable imaging with higher resistance to evaporation than water droplets.

Multilocus sequence analysis, a rapid and accurate identification tool for taxonomic classification, evolutionary relationship and population biology of the genus Shewanella.

This paper establishes a multilocus sequence analysis (MLSA) method using six protein-coding genes to classify Shewanella strains, revealing evolutionary relationships and population biology.

SIRT2 and lysine fatty acylation regulate the oncogenic activity of K-Ras4a

This study identifies lysine fatty acylation as a regulatory mechanism for K-Ras4a, showing that SIRT2-mediated defatty-acylation promotes oncogenic activity by enhancing endomembrane localization and interaction with A-Raf.