Author

S. R. Denmeade

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Gupta· 1 shared A. M. De Marzo· 1 shared A. Vaghasia· 1 shared B. Ozbek· 1 shared C. V. Dang· 1 shared E. S. Antonarakis· 1 shared J. Chen· 1 shared J. L. Hicks· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Gupta

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1 paper

Recent·Most cited

Cancer BiologybioRxivFeb 20, 2023

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

J. Chen, Q. Zheng, J. L. Hicks…·A. M. De Marzo

The paper develops a method to spatially quantify mitochondrial DNA copy number in cancer tissues and finds increased mtDNAcn in prostate cancer progression, linked to MYC activity.

DOI 10.1172/jci.insight.169868

humanspatial transcriptomics

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