BiophysicsbioRxiv
Site-specific effects of neurosteroids on GABAA receptor activation and desensitization
Y. Sugasawa, W. W. Cheng, J. Bracamontes…·A. Evers
This study identifies how neurosteroids interact with three distinct sites on the GABAA receptor, influencing activation and desensitization, and shows that site-specific binding determines their functional effects.
DOI 10.7554/elife.55331