BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Microtubule Binding Kinetics of Membrane-bound Kinesin Predicts High Motor Copy Numbers on Intracellular Cargo
R. Jiang, S. R. Vandal, S. Park…·W. O. Hancock
The paper measures the microtubule binding kinetics of membrane-bound kinesin-1 motors and finds that motor reattachment is not limited by diffusion but by intrinsic binding rates, predicting high motor copy numbers for long-range vesicle transport.
DOI 10.1073/pnas.1916204116