Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function
A. Roman-Fernandez, M. Mansour, F. G. Kugeratski…·D. M. Bryant
This study identifies PODXL as a decoy receptor for GAL3, revealing its role in promoting metastasis through integrin-based invasion and differential cortical targeting regulated by ubiquitination.