Author

M. Mansour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Alqarihi· 1 shared A. E. Warrington· 1 shared A. Howard· 1 shared A. Katoch· 1 shared A. Roman-Fernandez· 1 shared A. S. Ibrahim· 1 shared A. Trinquand· 1 shared C. J. Miller· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Alqarihi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of Polycomb Repressive Complex 2 function causes asparaginase resistance in T-acute lymphoblastic leukemia through decreased WNT pathway activity

T. Lefeivre, C. Tudose, T.-I. Grosu, L. Jones, T. Leon, K. Wynne, G. Oliviero, O. Smith, A. Trinquand, M. Mansour, C. Ryan, J. Bond

The paper identifies that PRC2 loss in T-ALL reduces WNT pathway activity, leading to asparaginase resistance, which can be overcome by proteasome inhibition.

bioRxiv · Aug 4, 2023 · PreprintCancer Biology

Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function

A. Roman-Fernandez, M. Mansour, F. G. Kugeratski, J. Anand, E. Sandilands, L. Galbraith, K. Rakovic, E. C. Freckmann, E. M. Cumming, J. Park, K. Nikolatou, S. Lilla, R. Shaw, D. Strachan, S. Mason, , D. M. Bryant

This study identifies PODXL as a decoy receptor for GAL3, revealing its role in promoting metastasis through integrin-based invasion and differential cortical targeting regulated by ubiquitination.

bioRxiv · Nov 4, 2022 · PreprintCell Biology

Selective Vulnerability of Senescent Glioblastoma Cells to Bcl-XL Inhibition

M. Rahman, I. E. Olson, M. Mansour, L. P. Carlstrom, R. Sutiwisesak, R. Saber, K. Rajani, A. E. Warrington, A. Howard, M. Schroeder, S. Chen, P. A. Decker, Y. Zhu, I. F. Parney, S. Burma, , E. F. Sananikone

This study identifies Bcl-XL inhibition as a selective vulnerability of senescent glioblastoma cells following radiation or TMZ treatment.

bioRxiv · Jun 3, 2020Cancer Biology

Alexidine dihydrochloride has broad spectrum activities against diverse fungal pathogens

Z. Mamouei, A. Alqarihi, S. Singh, S. Xu, M. Mansour, A. S. Ibrahim, P. Uppuluri

This study identifies Alexidine dihydrochloride as a broad-spectrum antifungal drug effective against multiple fungal pathogens and preformed biofilms.

bioRxiv · Oct 3, 2018Microbiology