Author

S. Ramakumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Singh· 1 shared D. Dey· 1 shared G. L. Conn· 1 shared H. Bansia· 1 shared N. H. Yennawar· 1 shared P. Mahanta· 1 shared P. R. Singh· 1 shared R. Rajmani· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. Singh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mycobacterium tuberculosis methyltransferase perturbs host epigenetic programming to promote bacterial survival

P. R. Singh, V. Dadireddy, S. Udupa, S. Kalladi, S. Shee, S. Khosla, R. Rajmani, A. Singh, S. Ramakumar, V. Nagaraja

This study shows that Mtb methyltransferase Rv2067c modifies host histone H3K79 methylation, inhibiting apoptosis and enhancing necrosis to promote bacterial survival.

bioRxiv · Feb 24, 2023 · PreprintMicrobiology

Targeted redesign of suramin analogs for novel antimicrobial lead development

D. Dey, S. Ramakumar, G. L. Conn

This paper develops a computational framework to design suramin analogs with specific antiviral and antibacterial activity by virtual screening against viral and bacterial protein targets.

bioRxiv · May 17, 2021Microbiology

Small Glycols Discover Cryptic Pockets on Proteins for Fragment-based Approaches

H. Bansia, P. Mahanta, N. H. Yennawar, S. Ramakumar

This study shows small glycols can identify cryptic pockets on proteins, aiding fragment-based drug design for previously undruggable targets.

bioRxiv · Aug 23, 2020Biophysics