Cancer BiologybioRxivPreprint
Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells
S. S. Chopra, A. Jenney, A. Palmer…·P. K. Sorger
The paper shows that combining mTOR and PIKK inhibitors kills triple-negative breast cancer cells by exploiting replication and checkpoint vulnerabilities.
DOI 10.1101/700625