BiophysicsbioRxiv
Characterizing the conformational free-energy landscape of RNA stem-loops using single-molecule field-effect transistors
S. S. Jang, S. Dubnik, J. Hon…·R. L. Gonzalez
This study uses single-molecule field-effect transistors to analyze the conformational free-energy landscape of RNA stem-loops, revealing a rugged landscape with unfolding timescales of 1-200 ms.
DOI 10.1021/jacs.2c10218