Author

S. S. Sarkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. V. Trivedi· 2 shared J. A. Spudich· 2 shared K. M. Ruppel· 2 shared A. S. Adhikari· 1 shared C. S. Rogers· 1 shared D. Bernstein· 1 shared D. Song· 1 shared E. M. Green· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

D. V. Trivedi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivJan 31, 2019

Hypertrophic cardiomyopathy mutations at the folded-back sequestered β-cardiac myosin S1-S2 and S1-S1 interfaces release sequestered heads and increase myosin enzymatic activity

A. S. Adhikari, D. V. Trivedi, S. S. Sarkar…·K. M. Ruppel

This study shows HCM mutations at specific myosin interfaces increase accessible heads and myosin activity, contributing to hypercontractility.

DOI 10.1038/s41467-019-10555-9

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivMar 10, 2018

Mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin

R. L. Anderson, D. V. Trivedi, S. S. Sarkar…·J. A. Spudich

The paper shows that mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin, linking mutations to cardiomyopathy mechanisms.

DOI 10.1073/pnas.1809540115

humanproteomics

𝕏 PostBluesky