Cell BiologybioRxiv
Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
S. Schwörer, M. Ros, K. M. Tsanov…·C. B. Thompson
The paper shows hypoxia enhances the inflammatory fibroblast phenotype in pancreatic cancer through HIF-1 activation, promoting tumor progression.
DOI 10.1158/0008-5472.can-22-2316