Beneficial Effects of Bempedoic Acid Treatment in Polycystic Kidney Disease Cells and Mice
K. R. Hallows, H. Li, B. Saitta, S. Sepehr, P. Huang, J. Pham, J. Wang, V. Mancino, E. J. R. Chung, S. L. Pinkosky, N. M. Pastor-Soler
This study shows that bempedoic acid reduces cyst growth in ADPKD cells and mice, and combining it with tolvaptan enhances therapeutic effects.
bioRxiv · Aug 9, 2022Pathology