Author

S. Shave

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

M. Auer· 2 shared D. Ceccarelli· 1 shared D. Evans· 1 shared F. Sicheri· 1 shared I. Perez-Pi· 1 shared J. Koszela· 1 shared M. Tyers· 1 shared N. Pham· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

M. Auer

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2 papers

Recent·Most cited

PyBindingCurve, simulation and curve fitting to complex binding systems at equilibrium.

S. Shave, Y.-K. Chen, N. T. Pham, M. Auer

PyBindingCurve simulates and fits equilibrium binding systems, revealing that homodimers are more easily inhibited and depleted than heterodimers under specific conditions.

bioRxiv · Nov 6, 2020Biophysics

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

J. Koszela, N. Pham, D. Evans, S. Mann, I. Perez-Pi, S. Shave, D. Ceccarelli, F. Sicheri, M. Tyers, M. Auer

This paper introduces a fluorescent confocal on-bead assay to real-time track ubiquitination cascades and identifies new inhibitor activities against Ube1.

bioRxiv · Feb 21, 2018Biochemistry