D. Evans

The Green Band: Using Production and Catch to Judge Distortive Pressure on an Ecosystem

The paper introduces the 'Green Band' concept to assess fishing pressure's impact on ecosystem structure using catch and production data across four case studies.

MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model

This paper shows that combining MYC and p53-R270H mutations in a mouse model generates high-grade serous ovarian and uterine serous carcinomas with human-like genetic and transcriptomic features.

E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

This study shows that HPV E7 represses miR-203, leading to LASP1 upregulation and promoting proliferation in HPV-positive cervical cancer.

Temporal control by co-factors prevents kinetic trapping in retroviral Gag lattice assembly

This study uses a reaction-diffusion model to show that co-factors like IP6 delay Gag lattice assembly, preventing kinetic trapping and enabling productive lattice formation.

The City Nature Challenge - A global citizen science phenomenon contributing to biodiversity knowledge and informing local government practices

The paper evaluates the City Nature Challenge's contribution to biodiversity knowledge and local government practices through a case study and framework development.

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

This study shows that HPV exploits KATP channels to promote cervical cancer cell proliferation through MAPK/AP-1 signaling.

Topological digestion drives time-varying rheology of entangled DNA fluids

This study investigates DNA-based complex fluids that undergo enzymatic topological changes, showing time-dependent rheological behavior controlled by restriction endonuclease reactions.

Generated randomly and selected functionally? The nature of enterovirus recombination

This study investigates the factors influencing recombination in poliovirus, finding that genome function and fitness, rather than sequence identity or structure, determine the identity of recombinant progeny.

Detection of Chemotherapy-Resistant Pancreatic Cancer Using a Glycan Biomarker

This paper identifies sTRA as a glycan biomarker for chemotherapy-resistant pancreatic cancer, showing its presence correlates with poor treatment response in multiple systems.

CpG-creating Mutations are Costly in Many Human Viruses

The paper examines the cost of CpG-creating mutations in various human viruses using existing genomic data and finds they are generally costly.

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

This paper introduces a fluorescent confocal on-bead assay to real-time track ubiquitination cascades and identifies new inhibitor activities against Ube1.