Cell BiologybioRxiv
Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)
K. Watanabe, K. Morishita, X. Zhou…·H. Ichijo
The paper identifies poly(ADP-ribose) as a regulator of ASK3 phase separation, enabling osmotic stress recognition and cell volume regulation.
DOI 10.1038/s41467-021-21614-5