Author

M. Koike

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Komatsu· 2 shared M. Yokota· 2 shared Y.-s. Sou· 2 shared A. H. El-Gowily· 1 shared A. Kuma· 1 shared C. Hata· 1 shared F. M. Omar· 1 shared H. Ichijo· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

M. Komatsu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Importin α Characterizes a Micronuclear Environment Associated with Genomic Instability in Human Cancer Cells

Y. Miyamoto, R. Kisanuki, R. Oshima, S. H. Yoshimura, M. Yokota, K. Maehara, C. Hata, T. Tachibana, H. Kimura, M. Koike, Y. Ohkawa, T. Katagiri, Y. Yoneda, M. Oka, H. Saitoh

The paper identifies importin α as a marker of a distinct micronuclear environment in cancer cells, associated with genomic instability and immune evasion.

Journal of Cell Science · Apr 27, 2026Peer-reviewedCell Biology

Droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show slower inner fluidity

F. M. Omar, Y. Ichimura, S. Kageyama, A. H. El-Gowily, Y.-s. Sou, M. Koike, N. N. Noda, M. Komatsu

This study investigates how ALS/FTD-related p62 mutations affect liquid droplet properties, finding that some mutants show reduced Nrf2 activation and delayed turnover, while all exhibit slower inner fluidity.

bioRxiv · Jun 7, 2021Cell Biology

Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)

K. Watanabe, K. Morishita, X. Zhou, S. Shiizaki, Y. Uchiyama, M. Koike, I. Naguro, H. Ichijo

The paper identifies poly(ADP-ribose) as a regulator of ASK3 phase separation, enabling osmotic stress recognition and cell volume regulation.

bioRxiv · Apr 20, 2020Cell Biology

Autophagy controls lipid droplet formation by fine-tuning NCoR1 levels

M. Komatsu, Y.-S. Sou, M. Koike, N. Mizushima, S. Waguri, S. Terai, A. Kuma, T. Saito, S.-s. Takahashi, T. Yabe

This study shows autophagy regulates lipid droplet formation by modulating NCoR1 levels, affecting LXR target gene expression and lipid metabolism in the liver.

bioRxiv · Aug 1, 2019 · PreprintCell Biology

Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent pathway of apoptosis

H. Tanaka, T. Okazaki, M. Yokota, M. Koike, Y. Okada, Y. Fujiki, Y. Gotoh

This study shows peroxisomes regulate mitochondrial dynamics and apoptosis by affecting Drp1-mediated fission and caspase activation.

bioRxiv · Sep 3, 2018Cell Biology