Y. Uchiyama

This study identifies BNIP3 as a mediator of DNA damage response signaling to mitochondria, which promotes senescence by altering mitochondrial structure and metabolism to increase p16 expression.

This study uses single-cell RNA-Seq and TCR-Seq to show HTLV-1-infected T-cells transition into highly activated ATL cells with Treg signatures and upregulated HLA class II, enabling immune evasion.

The paper shows SOX2 regulates HERV-K transcription and retrotransposition in stem cells, suggesting a role in embryonic protection while limiting genomic harm.

The paper identifies poly(ADP-ribose) as a regulator of ASK3 phase separation, enabling osmotic stress recognition and cell volume regulation.

This study shows that Bacteroides uniformis in the gut enhances endurance exercise performance by increasing gluconeogenesis through acetate and propionate production.

This study investigates the toxicokinetics of citreoviridin in swine and predicts human toxicokinetics by comparing in vitro and in vivo results, showing higher metabolism in humans.