SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta
M. Kirchenwitz, S. Stahnke, S. Prettin, M. Borowiak, C. Birchmeier, K. Rottner, T. E. B. Stradal, A. Steffen
The paper identifies SMER28 as a compound that inhibits PI3K p110 delta and disrupts receptor tyrosine kinase signaling, leading to autophagy induction and reduced cell growth.
bioRxiv · Dec 10, 2021Cell Biology