Author

S.-t. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

M. Bose· 2 shared M. Yazdanifar· 2 shared P. Grover· 2 shared P. Mukherjee· 2 shared R. Zhou· 2 shared A. J. Sanders· 1 shared A. W. Truman· 1 shared C. Brouwer· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

M. Bose

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2 papers

Recent·Most cited

Tumor -Associated MUC1 Regulates TGF-β Signaling and Function in Pancreatic Ductal Adenocarcinoma

P. Grover, S. Nath, M. Bose, A. J. Sanders, C. Brouwer, N. Fnu, R. Zhou, M. Yazdanifar, M. Ahmed, S.-t. Wu, A. W. Truman, P. Mukherjee

This study shows that high tMUC1 expression in PDA correlates with altered TGF-β signaling, promoting tumor growth and resistance to TGF-β therapy.

bioRxiv · Apr 29, 2020 · PreprintCancer Biology

Overcoming Immunological Resistance Enhances the Efficacy of a Novel anti-tMUC1 CAR T Cell Treatment Against Pancreatic Ductal Adenocarcinoma

M. Yazdanifar, R. Zhou, P. Grover, C. Williams, M. Bose, L. J. Moore, S.-t. Wu, R. Chi, J. Maher, D. Dreau, P. Mukherjee

This study develops a novel tMUC1-targeting CAR T cell therapy for pancreatic ductal adenocarcinoma and shows that combining it with inhibitors of IDO1, COX1/2, and Gal-9 enhances its efficacy against resistant tumors.

bioRxiv · May 20, 2019Cancer Biology