NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
N. Furthmann, L. Angersbach, V. Bader, A. Blusch, S. Goel, A. Sanchez-Vicente, L. J. Krause, P. Grover, V. A. Trinkaus, E. M. van Well, M. Jaugstetter, K. Tschulik, R. B. Damgaard, C. Saft, G. Ellrichmann, , K. F. Winklhofer
This study identifies a NF-κB-independent role of NEMO in proteostasis by promoting aggrephagy through co-condensation with p62.
bioRxiv · Jun 5, 2023 · PreprintCell Biology