Cell BiologyCytoskeletonPeer-reviewed
The ability of the LIMD1 and TRIP6 LIM domains to bind to f-actin under strain is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1.
Samriddha Ray, Chamika De Silva, Ishani Dasgupta…·Dannel McCollum
This study shows that TRIP6 and LIMD1 bind to strained actin, enabling their localization to adherens junctions and interaction with LATS1, a key Hippo pathway kinase.