Author

Samuel Sacco

California Institute of TechnologyPrimary ORCID profile (0000-0003-1227-8934 · 14 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Samuel SaccoiD14 papers · University of California, Santa Cruz

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Alon HerschhorniD· 1 shared Durgadevi ParthasarathyiD· 1 shared Héctor CerveraiD· 1 shared Joseph SodroskiiD· 1 shared Karunakar Reddy PothulaiD· 1 shared Katarzyna JanowskaiD· 1 shared Kim-Marie A. DamiD· 1 shared Michael D. BridgesiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alon HerschhornORCID

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1 paper

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedAug 26, 2024

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies

Durgadevi Parthasarathy, Karunakar Reddy Pothula, Kim-Marie A. Dam…·Alon Herschhorn

This paper shows that some HIV-1 transmitted/founder Envs are incompletely closed, making them sensitive to antibodies targeting open conformations, and highlights the importance of Env conformational flexibility for bnAb neutralization.

32 citationstop 4%

humanstructural biology

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