BiochemistryNature Chemical BiologyPeer-reviewed
Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53
Kim Wendrich, Kai Gallant, Sarah Recknagel…·Malte Gersch
This study identifies USP53 and USP54 as active deubiquitinases specific for K63-linked polyubiquitin, revealing their role in regulating tricellular junctions and correcting previous annotations of them as pseudo-enzymes.
28 citations