Author

Sascha Dlugosz

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Frank Zimmermann· 1 shared Joachim WittbrodtiD· 1 shared Marc FreicheliD· 1 shared Rebekka MedertiD· 1 shared Tanja Kellner· 1 shared Thomas ThumbergeriD· 1 shared Tinatini TavhelidseiD· 1 shared Tobias HubiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Frank Zimmermann

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1 paper

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedDec 12, 2022

Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice

Rebekka Medert, Thomas Thumberger, Tinatini Tavhelidse…·Marc Freichel

This study demonstrates that 5-biotinylation of donor DNA enhances single-copy HDR in mice, achieving 19-26% efficiency in generating conditional alleles.

15 citations

mouseexperimental assay

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