Rebekka Medert

This study shows JPT2/HN1L is essential for NAADP-mediated Ca2+ release in T cells but not in cardiomyocytes, platelets, or mast cells.

This paper describes a method to efficiently generate and identify CRISPR/Cas9-mediated single-cell knockout clones in murine cell lines within 3-4 weeks.

This study demonstrates that 5-biotinylation of donor DNA enhances single-copy HDR in mice, achieving 19-26% efficiency in generating conditional alleles.

The paper introduces hei-tag, a tag that enhances CRISPR/Cas9 and base editor efficiency across multiple species and applications.