ImmunologybioRxivPreprint
Targeting ion channel TRPM7 promotes the thymic development of Regulatory T cells by increasing IL-2-dependent STAT5 activation
Suresh K. Mendu, Michael S. Schappe, Emily K. Moser…·Bimal N. Desai
This study shows that inhibiting TRPM7 increases Treg cell development by enhancing IL-2-dependent STAT5 activation and Foxp3 expression.
DOI 10.1101/330233